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Delayed reporting of concussions may lead to prolonged post-concussion symptoms

According to a study published in this month’s Journal of Athletic Training, athletes who wait to report a concussion may experience prolonged recovery times. Researchers determined that athletes who delay post-concussion treatment missed close to one more week of activity than those who received immediate treatment. Athletes who do not receive immediate treatment are at risk for further damage to the brain and will most likely take much longer to recover. Previous research has also supported...Read more

DHA helps improve kidney cancer therapy according to new study

According to a new study published in the journal Molecular Cancer Therapeutics, researchers demonstrate that docosahexaenoic acid (DHA) helps reduce renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib.  Regorafenib is one of a new generation of anti-cancer therapies that attack tyrosine kinases. Unfortunately, kidney cancers mutate to resist these therapies. However, DHA metabolites called...Read more

Study demonstrates nutritional supplements improve efficacy of antidepressants

According to an evidence review published earlier this week in the American Journal of Psychiatry, researchers confirmed that certain nutritional supplements can increase the efficacy of antidepressants for individuals with clinical depression. Researchers at Harvard and the University of Melbourne examined 40 clinical trials along with a systematic review of the evidence for nutrient supplements that are used as adjuncts to help with clinical depression. As a result, fish oil, SAMe,...Read more

New study finds vitamin D improves heart function

According to a new study published Monday in the Journal of the American College of Cardiology, researchers demonstrated that vitamin D improves heart function in patients with chronic heart failure. Heart failure affects more than 23 million people worldwide. This statistic emphasizes the significance of this new study because it presents the first evidence that vitamin D supplementation can improve heart function of people with heart failure. The findings could make a meaningful difference in...Read more

New study shows higher doses of omega 3 fatty acids, specifically EPA, are beneficial for depression

Depression is a major cause of disease burden worldwide, affecting approximately 350 million people. For quite some time now, fish oil supplementation has been a recommended adjunct for helping with major depressive disorder (MDD). According to a new meta-analysis published two weeks ago in Translational Psychiatry, researchers have further confirmed the link between intake of omega-3 fatty acids and the reduction in major depressive disorder. This meta-analysis consisted of 13...Read more

New study reveals individuals with metabolic syndrome may require more vitamin E

New research published just two days ago in the American Journal of Clinical Nutrition demonstrated that approximately one-third of Americans who have metabolic syndrome do not absorb dietary vitamin E as effectively as healthy individuals. Vitamin E is a potent antioxidant that is essential to overall health. It is estimated that 35% of Americans have metabolic syndrome, which is characterized by having at least three of the following traits: excess abdominal fat, elevated blood pressure, low...Read more

Chemical exposure may be linked to rising rates in diabetes and obesity

According to a statement issued three days ago by the Endocrine Society, their summary links endocrine-disrupting chemical exposure to two of our biggest public health risks, diabetes and obesity. This news builds upon the Endocrine Society’s 2009 report, which examined the scientific evidence on endocrine-disrupting chemicals (EDCs) and the health risks associated with them. Since 2009, additional research has demonstrated that exposure to EDCs is associated with an increased risk of diabetes...Read more

Low vitamin D associated with age-related cognitive decline and dementia

In a new study published earlier this month in JAMA Neurology, researchers demonstrated a significant association between vitamin D insufficiency and cognitive decline that is specifically seen in Alzheimer's disease and dementia. The results reinforce the importance of identifying vitamin D insufficiency among the elderly. Here, low vitamin D levels were associated with significantly faster rates of decline in memory and executive function performance. This study included approximately...Read more

Resveratrol helps to stabilize Alzheimer's disease biomarker

A new study published last week in the journal Neurology demonstrated that long-term, high-dose resveratrol stabilized amyloid-beta40 (Abeta40) in patients with mild to moderate Alzheimer's disease. This biomarker declines when the disease progresses. Even though this is a single, small study, it is the largest and longest nationwide human clinical trial of high-dose resveratrol to date. The clinical trial was a randomized, phase II, placebo-controlled, double blind study in patients with mild...Read more

New study finds high prevalence of pre-diabetes and diabetes in the U.S.

According to a new study published in JAMA just three days ago, the increasing prevalence of diabetes may be leveling off. That being said, in 2011 through 2012, the estimated prevalence of diabetes among U.S. adults was 14% and the prevalence of pre-diabetes was 38%, which means about half of the U.S. adult population has either diabetes or pre-diabetes. Diabetes is a major cause of illness and death and is still a significant problem in the U.S. The healthcare costs associated with diabetes...Read more

Vitamin D and its role in macular degeneration

Vitamin D has been extensively researched for its benefits in bone health, cancer, inflammation, and the immune system. A new study published in JAMA Ophthalmology last week found that vitamin D may be a critical player in eye health in the prevention of age-related macular degeneration, specifically among women who are genetically susceptible. This may have to do with its role in inflammation, which is believed to be involved in the development of macular degeneration. Macular...Read more

Are you allergic to the fruits and vegetables you eat? You may actually be reacting to the antibiotic residues in the food.

A recent article published in Annals of Allergy, Asthma and Immunology discusses a case of a 10 year-old girl who had an anaphylactic reaction after eating blueberry pie. She had a history of asthma and seasonal allergies, and known allergies to penicillin and cow's milk, but she was not aware of being allergic to any of the ingredients in the pie. After much testing, it was discovered that the reaction was caused by streptomycin-contaminated blueberry. Streptomycin is a well-known antibiotic,...Read more

Green tea polyphenols protect spinal cord neurons against oxidative stress

Green tea polyphenols are a potential new aid for the recovery and regeneration of neurons after spinal cord injury. Several factors contribute to pathological changes secondary to spinal cord injury, with oxidative stress having a very important role. The formation of reaction oxygen species is the basic response to disease and trauma that contributes significantly to the injury. As a result, oxidative stress and inflammation cause the death of neurons and are the main processes leading to...Read more

Can probiotics help prevent obesity?

In a recent study, researchers at Vanderbilt tested a bacteria that can produce a “therapeutic compound” in the gut. The results showed that it stopped weight gain, insulin resistance and other health complications.  Past research has demonstrated that gut bacteria plays a role in the development of obesity, diabetes, and cardiovascular disease.  According to Sean Davis, PhD, assistant professor of pharmacology at Vanderbilt, “The types of bacteria you have in your gut influence your...Read more

Is niacin safe?

There has been some recent negative news about niacin based on the HPS2-THRIVE study, and now we see it again, this time in the New England Journal of Medicine.  Let’s take a closer look at all of this.  First, in the recent HPS2-THRIVE study, which examined an investigational drug from Merck, the researchers state that niacin does not provide any benefits. The drug they looked at is a combination of extended-release niacin and laropiprant, a drug which partially blocks the flushing...Read more

Examining immune-related disorders and microbial balance

It has become increasingly clear that many diseases are triggered or influenced by changes in bacterial populations in the gut. The general view up until now has been that bacteria stimulate the immune system, which leads to inflammation or autoimmune diseases. In a recent study published in Immunity, researchers have painted a more complex picture. The immune system of the gastrointestinal tract not only prevents the invasion of pathogens, but it is more actively involved in the balance...Read more

The human gut has only a limited ability to convert folic acid to 5-MTHF.

There has been a lot of press on the link between MTHFR (methylenetetrahydrofolate reductase) gene mutations and chronic disease. This has resulted in a great deal of concern with the particular form of folate that doctors are giving to their patients. As Director of Clinical and Product Support here at Designs for Health, I personally speak to approximately five doctors a day about this very topic. According to a recent study in the American Journal of Clinical Nutrition, the human gut appears...Read more

New study demonstrates effect of dietary supplements on clinical aspects of autism

Posted on Fri, Apr 28, 2017 @ 01:42 PM

Autism spectrum disorder (ASD) has an unclear cause but is associated with various genetic, neurologic, metabolic, and immunologic factors. Although there is no definitive treatment, there has been increasing use of dietary interventions and nutritional support in these patients. For example, many children with ASD take nutritional supplements and follow specific diets such as a gluten-free and casein-free (GFCF) diet.

Pharmaceutical and behavioral therapies are often used, but their success is limited. This can be due to the high variability of autism as well as adverse reactions to medications.

According to a review published seven days ago in Brain Development, researchers demonstrated the clinical efficacy and safety of dietary supplements in children with autism.

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Tags: supplements, Vitamin C, autism, vitamin d, children's health, gut health, autism spectrum disorder, essential fatty acids

New study demonstrates magnesium’s role in fracture prevention

Posted on Fri, Apr 21, 2017 @ 10:08 AM

According to a new study published in the European Journal of Epidemiology, researchers identified an association between low serum magnesium levels and an increased risk of fracture. Most patients with osteoporosis or osteopenia who want to optimize their bone health are told by their traditional doctor to take calcium and vitamin D supplementation, yet most never recommend magnesium to their patients. Alternative and integrative practitioners, on the other hand, recognize the essential role of magnesium in several cellular processes, including it being a major component in bone (50%).

A magnesium insufficiency is seen in most patients, which can be crucial in addressing and preventing disability in middle-aged to elderly people resulting from fractures.

Bone fractures are one of the leading causes of disability especially among the elderly. It is well-known that calcium, vitamin D, vitamin K and trace minerals all play an important role in bone health.

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Tags: magnesium, calcium, vitamin d, bone health, collagen, eldery

New study demonstrates bovine colostrum decreases intestinal permeability in athletes

Posted on Fri, Apr 14, 2017 @ 07:57 AM

An interesting study was just published 6 days ago in Nutrients on intestinal permeability and athletes. This is a compelling follow-up to a similar article I shared last July in the American Journal of Clinical Nutrition on heavy exercise-induced intestinal permeability in athletes.

When one thinks of nutritional supplements in athletes, they usually think of nutrients that enhance energy and sports performance. However, athletes commonly suffer from gut issues that are often not identified or addressed. 'Leaky gut' occurs from dysfunction in the intestinal barrier. This intestinal barrier in the gut is only one cell layer thick. It is essential for the absorption of nutrients and preventing large molecules and bacteria from getting into the blood stream. This is a particular problem for those taking part in heavy exercise or any form of vigorous strength training, such as CrossFit athletes, strongman competitors, and powerlifters, and can lead to gut issues in athletes as well as more serious conditions such as inflammatory bowel and autoimmune disorders.

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Tags: exercise, gut health, leaky gut

New study demonstrates enhanced cognition and cerebrovascular function with resveratrol

Posted on Fri, Apr 07, 2017 @ 09:40 AM

Alzheimer’s disease and related disorders (ADRD) are a group of conditions that cause mild cognitive impairment (MCI) or dementia. These conditions affect one’s ability to function socially, personally, and professionally. It’s important to recognize that Alzheimer’s disease begins long before symptoms start, just like many other conditions. There is evidence that simple prevention strategies can reduce the risk of ADRD by as much as 50%.

The prevalence of dementia for those over 65 years of age is 14% in men and 32% in women. By the age of 80, 63% of those with dementia are women.

Resveratrol has been widely publicized for its cardiovascular health benefits. However, researchers believe it also has positive effects on the hippocampus, an area of the brain that is critical to functions such as memory, learning and mood.

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Tags: brain health, Resveratrol, Menopause, Alzheimer's

New study investigates potential mechanisms of serum-derived bovine immunoglobulin in patients with IBS

Posted on Fri, Mar 31, 2017 @ 09:30 AM

Irritable bowel syndrome (IBS) is a condition consisting of cramping, abdominal pain, bloating, gas, diarrhea and constipation. IBS is often debilitating and can affect many aspects of a person’s life, including their work, sleep and relationships.

A variety of factors have been associated with IBS, such as genetic susceptibility, infections, small bowel intestinal overgrowth, deficiencies in tight junction proteins, intestinal abnormalities with bile acid metabolism, changes in GI motility, visceral hypersensitivity, dysregulation of the interaction between the CNS and enteric nervous system, and even psychosocial factors.

An individual with IBS may need a combination of botanicals, enzymes, and probiotics to optimize the gastrointestinal environment. Certain diagnostic tests may also be beneficial, including stool testing as well as food antibody testing.

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Tags: IBD, Inflammation, inflammatory bowel disease, gut health

New study demonstrates sulforaphane’s influence on genetics and prostate cancer

Posted on Fri, Mar 24, 2017 @ 10:49 AM

According to a recent study published in the Journal of Nutritional Biochemistry, researchers identified a pathway where sulforaphane may influence long, non-coding RNAs.

This research provides evidence on how these RNAs may play a critical role in triggering the proliferation of cells to become malignant and metastasize. Previous research has demonstrated that long, non-coding RNAs have an essential role in cellular development and an epigenetic influence by controlling which genes are expressed. Researchers believe that when these are dysregulated, they can contribute to chronic disease and cancer.

In this study, researchers demonstrated that one long, non-coding RNA was decreased four-fold with the treatment of sulforaphane and is upregulated in prostate cancer. As a result, treatment with sulforaphane could normalize these long, non-coding RNA levels, which not only may help with cancer prevention but also with slowing cancer progression.

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Tags: prostate, curcumin, vitamin d, cancer, fish oil, genetics

New study demonstrates B vitamins may reduce the negative effects from air pollution

Posted on Fri, Mar 17, 2017 @ 04:10 PM

According to a new study published in PNAS, researchers at Columbia University demonstrated that B vitamins may play an essential role in reducing the impact of air pollution. This is the first study to show possible interventions that may prevent or minimize the adverse effects of air pollution. Specifically, it shows how preventive measures with B vitamins can influence particular pathways that may mitigate these adverse effects. 

The World Health Organization (WHO) estimates that approximately 92% of the population lives in places where air quality levels exceed the limits of 10 μg/m3. Air pollutants can deposit in the respiratory tract, which can result in lung and systemic inflammation. Although there has been substantial lowering of air pollution through large-scale emissions control policies over the past few decades, its negative health effects are still common and may contribute to many complex health issues.

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Tags: detox, detoxification, toxins

New study demonstrates blueberry supplementation helps improve brain function

Posted on Fri, Mar 10, 2017 @ 01:07 PM

Cognitive function declines with age as the body’s cells are more susceptible to damage and death. In addition, the body produces less energy due to slower metabolism and, as a result, cells are less able to produce antioxidants and soak up free radicals.

There is evidence that simple prevention strategies, such as a diet rich in plant-based foods, can help reduce the risk of dementia and preserve cognition. Flavonoids are an essential component contributing to these effects. Blueberries are rich in flavonoids, which contain powerful antioxidant and anti-inflammatory properties. While high intake of flavonoids has been shown to help mitigate age-related cognitive decline, human studies have been limited.

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Tags: brain health, anti-inflammatory, Antioxidant, Inflammation

New study identifies trigger associated with inflammatory and autoimmune conditions

Posted on Fri, Mar 03, 2017 @ 04:11 PM

According to a new study published last month, researchers have identified an inflammatory molecule associated with inflammatory disorders such as inflammatory bowel disease (IBD) and psoriasis. The findings of this study help to distinguish therapeutic targets for supporting and treating these types of conditions.

The researchers discovered that dying cells release IL-1, an inflammatory signal, which is the cause of the inflammation, and concluded that targeting this molecule may be an effective method of treatment. Thus, the study’s results suggest that targeting IL-1 could suppress inflammation associated with conditions such as atherosclerosis, MS, liver disease, pancreatitis, psoriasis, IBD, and infectious diseases.

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Tags: IBD, curcumin, Inflammation, autoimmune disease, inflammatory bowel disease, psoriasis

Low vitamin D levels increase risk of relapse in patients with ulcerative colitis

Posted on Fri, Feb 24, 2017 @ 12:02 PM

According to a new study published this month in the journal Clinical Gastroenterology and Hepatology, researchers discovered that lower levels of vitamin D were associated with an increased risk of a relapse in patients with ulcerative colitis (UC).

The role of vitamin D in autoimmunity and disease severity is well known; however, it has been unknown if it contributes to disease relapses and unclear if the flare-up was lowering vitamin D levels or if low vitamin D levels were causing the flare-up.

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Tags: IBD, vitamin d, inflammatory bowel disease, ulcerative colitis

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