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Delayed reporting of concussions may lead to prolonged post-concussion symptoms

According to a study published in this month’s Journal of Athletic Training, athletes who wait to report a concussion may experience prolonged recovery times. Researchers determined that athletes who delay post-concussion treatment missed close to one more week of activity than those who received immediate treatment. Athletes who do not receive immediate treatment are at risk for further damage to the brain and will most likely take much longer to recover. Previous research has also supported...Read more

DHA helps improve kidney cancer therapy according to new study

According to a new study published in the journal Molecular Cancer Therapeutics, researchers demonstrate that docosahexaenoic acid (DHA) helps reduce renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib.  Regorafenib is one of a new generation of anti-cancer therapies that attack tyrosine kinases. Unfortunately, kidney cancers mutate to resist these therapies. However, DHA metabolites called...Read more

Study demonstrates nutritional supplements improve efficacy of antidepressants

According to an evidence review published earlier this week in the American Journal of Psychiatry, researchers confirmed that certain nutritional supplements can increase the efficacy of antidepressants for individuals with clinical depression. Researchers at Harvard and the University of Melbourne examined 40 clinical trials along with a systematic review of the evidence for nutrient supplements that are used as adjuncts to help with clinical depression. As a result, fish oil, SAMe,...Read more

New study finds vitamin D improves heart function

According to a new study published Monday in the Journal of the American College of Cardiology, researchers demonstrated that vitamin D improves heart function in patients with chronic heart failure. Heart failure affects more than 23 million people worldwide. This statistic emphasizes the significance of this new study because it presents the first evidence that vitamin D supplementation can improve heart function of people with heart failure. The findings could make a meaningful difference in...Read more

New study shows higher doses of omega 3 fatty acids, specifically EPA, are beneficial for depression

Depression is a major cause of disease burden worldwide, affecting approximately 350 million people. For quite some time now, fish oil supplementation has been a recommended adjunct for helping with major depressive disorder (MDD). According to a new meta-analysis published two weeks ago in Translational Psychiatry, researchers have further confirmed the link between intake of omega-3 fatty acids and the reduction in major depressive disorder. This meta-analysis consisted of 13...Read more

New study reveals individuals with metabolic syndrome may require more vitamin E

New research published just two days ago in the American Journal of Clinical Nutrition demonstrated that approximately one-third of Americans who have metabolic syndrome do not absorb dietary vitamin E as effectively as healthy individuals. Vitamin E is a potent antioxidant that is essential to overall health. It is estimated that 35% of Americans have metabolic syndrome, which is characterized by having at least three of the following traits: excess abdominal fat, elevated blood pressure, low...Read more

Chemical exposure may be linked to rising rates in diabetes and obesity

According to a statement issued three days ago by the Endocrine Society, their summary links endocrine-disrupting chemical exposure to two of our biggest public health risks, diabetes and obesity. This news builds upon the Endocrine Society’s 2009 report, which examined the scientific evidence on endocrine-disrupting chemicals (EDCs) and the health risks associated with them. Since 2009, additional research has demonstrated that exposure to EDCs is associated with an increased risk of diabetes...Read more

Low vitamin D associated with age-related cognitive decline and dementia

In a new study published earlier this month in JAMA Neurology, researchers demonstrated a significant association between vitamin D insufficiency and cognitive decline that is specifically seen in Alzheimer's disease and dementia. The results reinforce the importance of identifying vitamin D insufficiency among the elderly. Here, low vitamin D levels were associated with significantly faster rates of decline in memory and executive function performance. This study included approximately...Read more

Resveratrol helps to stabilize Alzheimer's disease biomarker

A new study published last week in the journal Neurology demonstrated that long-term, high-dose resveratrol stabilized amyloid-beta40 (Abeta40) in patients with mild to moderate Alzheimer's disease. This biomarker declines when the disease progresses. Even though this is a single, small study, it is the largest and longest nationwide human clinical trial of high-dose resveratrol to date. The clinical trial was a randomized, phase II, placebo-controlled, double blind study in patients with mild...Read more

New study finds high prevalence of pre-diabetes and diabetes in the U.S.

According to a new study published in JAMA just three days ago, the increasing prevalence of diabetes may be leveling off. That being said, in 2011 through 2012, the estimated prevalence of diabetes among U.S. adults was 14% and the prevalence of pre-diabetes was 38%, which means about half of the U.S. adult population has either diabetes or pre-diabetes. Diabetes is a major cause of illness and death and is still a significant problem in the U.S. The healthcare costs associated with diabetes...Read more

Vitamin D and its role in macular degeneration

Vitamin D has been extensively researched for its benefits in bone health, cancer, inflammation, and the immune system. A new study published in JAMA Ophthalmology last week found that vitamin D may be a critical player in eye health in the prevention of age-related macular degeneration, specifically among women who are genetically susceptible. This may have to do with its role in inflammation, which is believed to be involved in the development of macular degeneration. Macular...Read more

Are you allergic to the fruits and vegetables you eat? You may actually be reacting to the antibiotic residues in the food.

A recent article published in Annals of Allergy, Asthma and Immunology discusses a case of a 10 year-old girl who had an anaphylactic reaction after eating blueberry pie. She had a history of asthma and seasonal allergies, and known allergies to penicillin and cow's milk, but she was not aware of being allergic to any of the ingredients in the pie. After much testing, it was discovered that the reaction was caused by streptomycin-contaminated blueberry. Streptomycin is a well-known antibiotic,...Read more

Green tea polyphenols protect spinal cord neurons against oxidative stress

Green tea polyphenols are a potential new aid for the recovery and regeneration of neurons after spinal cord injury. Several factors contribute to pathological changes secondary to spinal cord injury, with oxidative stress having a very important role. The formation of reaction oxygen species is the basic response to disease and trauma that contributes significantly to the injury. As a result, oxidative stress and inflammation cause the death of neurons and are the main processes leading to...Read more

Can probiotics help prevent obesity?

In a recent study, researchers at Vanderbilt tested a bacteria that can produce a “therapeutic compound” in the gut. The results showed that it stopped weight gain, insulin resistance and other health complications.  Past research has demonstrated that gut bacteria plays a role in the development of obesity, diabetes, and cardiovascular disease.  According to Sean Davis, PhD, assistant professor of pharmacology at Vanderbilt, “The types of bacteria you have in your gut influence your...Read more

Is niacin safe?

There has been some recent negative news about niacin based on the HPS2-THRIVE study, and now we see it again, this time in the New England Journal of Medicine.  Let’s take a closer look at all of this.  First, in the recent HPS2-THRIVE study, which examined an investigational drug from Merck, the researchers state that niacin does not provide any benefits. The drug they looked at is a combination of extended-release niacin and laropiprant, a drug which partially blocks the flushing...Read more

Examining immune-related disorders and microbial balance

It has become increasingly clear that many diseases are triggered or influenced by changes in bacterial populations in the gut. The general view up until now has been that bacteria stimulate the immune system, which leads to inflammation or autoimmune diseases. In a recent study published in Immunity, researchers have painted a more complex picture. The immune system of the gastrointestinal tract not only prevents the invasion of pathogens, but it is more actively involved in the balance...Read more

The human gut has only a limited ability to convert folic acid to 5-MTHF.

There has been a lot of press on the link between MTHFR (methylenetetrahydrofolate reductase) gene mutations and chronic disease. This has resulted in a great deal of concern with the particular form of folate that doctors are giving to their patients. As Director of Clinical and Product Support here at Designs for Health, I personally speak to approximately five doctors a day about this very topic. According to a recent study in the American Journal of Clinical Nutrition, the human gut appears...Read more

New study demonstrates patients with inflammatory bowel disease can reach remission with diet alone

Posted on Sun, Jan 08, 2017 @ 09:56 AM

Inflammatory-Bowel-Disease-woman.jpg

According to a new study published last week in the Journal of Clinical Gastroenterology, researchers demonstrated that diet alone can bring pediatric patients with active inflammatory bowel disease (IBD) into remission.

In this study, patients were put on a specific carbohydrate diet (SCD) for 12 weeks. This diet consisted of removing grains, dairy, processed foods and sugars, except for honey. At the end of the study, eighty percent of the patients showed significant improvement and achieved remission from following the diet alone.

According to a new study published last week in the Journal of Clinical Gastroenterology, researchers demonstrated that diet alone can bring pediatric patients with active inflammatory bowel disease (IBD) into remission.

In this study, patients were put on a specific carbohydrate diet (SCD) for 12 weeks. This diet consisted of removing grains, dairy, processed foods and sugars, except for honey. At the end of the study, eighty percent of the patients showed significant improvement and achieved remission from following the diet alone.

Studies like this which address the underlying cause of disease can be found in the current medical research, but you would never know it by visiting many doctors. Unfortunately, we see it all too often that there is a huge disconnect between medical research and the practice of traditional medicine when it comes to the management of chronic disorders.

This new study should change the paradigm of how gastroenterologists treat IBD. The typical allopathic approach is focused on symptom management, using various anti-inflammatory medications and biologics with serious potential side-effects. These approaches, of course, can provide substantial relief to the patient, but they do not address the cause of the conditions and some evidence suggests that these approaches may result in furthering the pathological process.

What appears to happen with most autoimmune conditions is that there are multiple triggers chronically stimulating the immune system over a long period of time in multiple ways and the immune system gets into an overloaded, overwhelmed state and loses its ability to function.

 

A Personal Story

In April 2015, a father of an 18 year old female reached out to me. His daughter was diagnosed with Crohn’s disease four months prior. She had one severe episode that resulted in a visit to the emergency room where she was treated with antibiotics and anti-inflammatory medications. Her father was searching for a natural, alternative approach to her health.

The patient had a long history of antibiotic treatment and eczema. When she first saw her gastroenterologist, she was anemic and her hs-CRP was significantly elevated at 92.2. The doctor simply stated the only solution was a biologic. In addition, the anemia was never addressed.

The current medical research demonstrates the significance of micronutrient deficiencies in IBD; however, many traditional doctors tell their patients that their condition is not related to diet. For example, in a study published in November 2015, researchers reported that micronutrient deficiencies are common in more than half of patients with IBD and have a clinical significance.

I assessed her nutrient status, which revealed deficiencies in iron, magnesium, and vitamin D, and addressed them appropriately. A study published last year demonstrated vitamin D deficiency and its association with increased Crohn’s disease severity. In addition, a separate study published in the United European Gastroenterology Journal reported the effects of vitamin D supplementation on intestinal permeability and disease markers in Crohn’s disease.

Additional testing revealed elevated inflammatory and immune markers as well as a dysbiosis of the gut microbiome, which are commonly associated with chronic disease states. 

The patient followed an elimination diet based upon food sensitivity results and avoided processed food. Her gut dysbiosis was addressed with specific antimicrobials, probiotics, glutamine, fish oil, proteolytic enzymes and antioxidants. At her two month follow up, her CBC was normal, hs-CRP dropped to 16.3, sed rate was 38, and vitamin D increased to 69.1 ng/ml. At the four month follow up, her hs-CRP dropped to a normal range 1.66 and sed rate was within normal limits at eight. Her dad’s response was “these results are incredible!” It’s interesting because when she had her two month follow up with the doctor, he was insistent on prescribing the biologic even though her labs had improved so much during this time. The doctor stated that he was impressed with the results but that this was a “temporary phenomena.” Today, this young college student is symptom-free and has been in clinical remission for over a year.

There is a time and a place for medications, but there remains a large disconnect between the medical research and what is experienced visiting a doctor in everyday practice. The research demonstrates the significance of nutrients and their essential role in chronic disease. Lifestyle choices and environmental exposures filtered through genetic predisposition are fundamental factors in IBD, and a successful treatment approach must include investigation into these factors.

By Michael Jurgelewicz, DC, DACBN, DCBCN

 

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GI Microb-X™ FloraMyces™ L-Glutamine OmegAvail™ TG1000 Inflammatone™

 

Source: Suskind, David L et al. Clinical and Fecal Microbial Changes With Diet Therapy in Active Inflammatory Bowel Disease. Journal of Clinical Gastroenterology, 2016 

 

Tags: Probiotics, IBD, Inflammation, glutamine, inflammatory bowel disease, specific carbohydrate diet, fish oil, enzymes

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