Alterations in gut microbiome have been associated with metabolic diseases such as obesity and type 2 diabetes; however, the changes in bacteria species or genomic composition are not clear. Previous animal studies have indicated that bacteria that are able to invade the epithelium may cause inflammation that drives metabolic disorders.
According to a new study published in the journal Cellular and Molecular Gastroenterology and Hepatology, researchers at Georgia State University have identified a correlation between bacteria invading the intestinal epithelium of the colon and the development of type 2 diabetes.
In this study, researchers used samples from patients at the Veteran's Administration Hospital in Atlanta. These individuals were at least 21 years old with no other health issues other than diabetes. They all had a colonoscopy in which two mucosal biopsies from the left colon were analyzed.Read More